introduction:the prevalence of atopic diseases has increased in recent decades dramatically. the most common aeroallergens in northeastern iran have not been fully defined. define the most common aeroallergens in allergic patients based on the skin prick test (spt) was aimed in this investigation.materials and methods:this cross-sectional study enrolled 1,006 allergic patients (aged 1–86 years)...

Introduction:The prevalence of atopic diseases has increased in recent decades dramatically. The most common aeroallergens in Northeastern Iran have not been fully defined. Define the most common aeroallergens in allergic patients based on the skin prick test (SPT) was aimed in this investigation.Materials and Methods:This cross-sectional study enrolled 1,006 allergic patients (aged 1–86 years)...

Allergy, airway hyperreactivity (AHR), and allergic asthma are risk factors of chronic obstructive pulmonary disease (COPD), a heterogeneous disease presenting with various phenotypes. An allergic phenotype of COPD, characterized by more severe respiratory symptoms and higher risk of acute exacerbations, was described recently.[1] Further investigations into the role of allergy in the pathogene...

More than 3 billion people worldwide are infected with parasitic worms called helminthes or suffer allergic disorders such as asthma, allergic rhinitis, food allergies and eczema. A common feature of these infectious or inflammatory conditions is the called allergic or “type 2” immune response. Type 2 immune responses are induced by and confer protection against helminthes, but can also play pa...

allergic fungal sinusitis (afs) has been clinicopathologically defined as a noninvasive form of fungal infection. this study was designed to distinguish afs among patients with chronic sinusitis who failed to respond to repeated courses of antibiotics and were therefore candidates for functional endoscopic sinus surgery (fess) in sari. allergic mucin and sinus lavage was collected during fess f...

This new regular feature will be focusing on the different methodologies used in the diagnosis of allergies, describing current assays and introducing novel approaches. Hypersensitivity reactions can be differentiated into IgEand non-IgE-mediated allergic but also non-allergic reactions. Over the next issues the different in vitro and in vivo diagnostic assays will be explained and the advantag...

the aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. in a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. demographic, clinical, and familial history were compared between two groups. there was no significant differences between variables like sex, age of onset ...

The best recognized intestinal manifestation of food allergy is food allergic (food-sensitive) enteropathy. The feature of enteropathy may include lymphocyte and plasma cell infiltration, epithelial abnormality, or crypt hyperplastic villous atrophy, and impairing absorption, enterophaty continues while the food remains in the diet, remitting on an exclusion diet, and usually recurring on food ...

Both genetic and environmental factors are important for the development of allergic diseases. However, a detailed understanding of how such factors act together is lacking. To elucidate the interplay between genetic and environmental factors in allergic diseases, we used a novel bioinformatics approach that combines feature selection and machine learning. In two materials, PARSIFAL (a European...